POST-OPERATIVE NEURODEVELOPMENTAL FINDINGS IN SYNDROMIC AND NON-SYNDROMIC CRANIOSYNOSTOSIS

ABBAS NEJAD, Enayatollah and NIKOOBAKHAT, Mehdi (2010) POST-OPERATIVE NEURODEVELOPMENTAL FINDINGS IN SYNDROMIC AND NON-SYNDROMIC CRANIOSYNOSTOSIS. Iranian Journal of Child Neurology, 3 (4). pp. 45-50.

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Abstract

Objective

To evaluate the developmental situation of children that undergo operation because of syndromic and non-syndromic craniosynostosis.

Materials & Methods

In this prospective study, 24 children (4 to 16 months of age) who underwent neurosurgeryical intervention because of non-syndromic (79%) and syndromic (21%) craniosynostosis were recruited. For psychological evaluation, the Bayley Scales of Infant Development-Second Edition (BSID-II) was applied one month before and one year after surgical correction. The scale consists of three parts, Mental Developmental Index (MDI), Psychomotor Developmental Index (PDI), and Behavior Rating Scale. The MDI and PDI yield age-standard scores (100 ± SD).

Results

Mean baseline BSID-II scores revealed a mild delay in mental and motor scores (MDI: 84.3±2.1; PDI: 80.5±4.2) in non-syndromic craniosynostosis and a moderate delay in mental and motor scores (MDI: 70.3±3.1; PDI: 64.3±1.7) in syndromic craniosynostosis. Mean postoperative BSID-II score revealed improved motor scores (MDI: 91.3±0.1; PDI: 91.3±0.2) in non-syndromic craniosynostosis and mean postoperative BSID-II score revealed a mild delay in mental scores and no change in PDI. Among children with syndromic craniosynostosis, mean BSID-II score indicated mild baseline deficits in both mental and motor scores post operatively.

Conclusion

Mental development and prognosis was better in non-syndromic

craniosynostosis comparing syndromic craniosynostosis. Surgery is

effective in neurodevelopmental growth in non syndromic types of

craniosynostosis but in syndromic type, remodeling surgery does not

significantly affect neurodevelopmental outcome.

Item Type: Article
Subjects: Open Archive Press > Medical Science
Depositing User: Unnamed user with email support@openarchivepress.com
Date Deposited: 08 Feb 2023 07:16
Last Modified: 11 Jul 2024 07:55
URI: http://library.2pressrelease.co.in/id/eprint/370

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