PECULIARITIES OF DIURNAL BLOOD PRESSURE PROFILE IN PATIENTS WITH ARTERIAL HYPERTENSION, PREDIABETESAND TYPE 2 DIABETES

The purpose of this study is to assess the features of diurnal blood pressure profile (DBPP) in patients with arterial hypertension (AH) and prediabetes or type 2 diabetes. The study included 133 patients with AH, 30 without disturbed carbohydrate metabolism, 73 with prediabetes and 30 with type 2 diabetes. All patients underwent 24-hour blood pressure monitoring (BPM) using the BPLab Vasotens complex. The study concluded that in patients with AH in combination with prediabetes the DBPP parameters were comparable to those of patients with AH and type 2 diabetes. Furthermore, in case of disturbed carbohydrate metabolism most parameters were reliably higher than those with isolated AH, at that the most significant differences were in the parameters of pulsatile, systolic and diastolic blood pressure (SBP and DBP), mainly at night. It is important that in patients with AH with disturbed carbohydrate metabolism a more pronounced «pressure load» was detected, predominantly at night. When assessing the diurnal profile in patients with AH with prediabetes, an unfavorable type of the «non-dipper» curve was more often detected, as in patients with type 2 diabetes. Thereby, in patients with AH in combination with prediabetes, unlike to patients without disturbed carbohydrate metabolism, there were more significant pathological changes in the parameters of the DBPP, which were comparable to those with AH and type 2 diabetes.