The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN

TALEBIAN, Ahmad and JAHANGIRI, Mohammad and RABIEE, Mahin Rabiee and ALAVI, Negin MASOUDI and AKBARI, Hossein Akbari and SADAT, Zohreh (2015) The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN. Iranian Journal of Child Neurology, 9 (2). pp. 29-35.

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Abstract

Objective

Detection of seizure, its etiology, and clinical types is important for guiding therapy. This study was designed to evaluate the etiology and clinical evaluations of neonatal seizures in Kashan, Iran.

Materials and Methods

The data of 100 hospitalized neonates with a complaint of seizures in Kashan City, from January 2006 to January 2011 were evaluated. The pediatric neurologist made the final diagnosis. The gestational age, neonate admission age, type of delivery, and laboratory and radiological investigations were reviewed from the medical records. The relation of seizure etiology and other variables were compared using the Chi-square test. All the statistical analyses were performed using SPSS (ver 11.5).

Results

A total of 100 neonates were hospitalized with a diagnosis of seizures. The overall incidence rate of seizures was 2.6 per 1,000 live births. A total of 59% of seizures happened in the first three days of life. The etiologies of seizures were hypoxicischemic encephalopathy (HIE) (36%), hyponatremia (12%), hypoglycemia (11%), intracranial hemorrhage (11%), infections (10%), hypocalcemia (8%), metabolic disorders (7%), the structural anomalies (5%), and hypomagnesaemia (4%). In 23% of neonates, no specific etiology was found and 23% had multiple etiologies. In 45% of neonates, the EEG was not recorded. The type of the seizures were focal-clonic (26%), tonic (25%), multifocal clonic (34%), subtle

(11%), and myoclonic (4%). The types of the seizure were unrelated to the paraclinical findings.

Conclusion

Neonatal seizures are common and HIE was the main cause of seizures in this study. The clinical evaluation of neonatal seizures needs improvement.

Item Type: Article
Subjects: Open Archive Press > Medical Science
Depositing User: Unnamed user with email support@openarchivepress.com
Date Deposited: 27 Mar 2023 06:15
Last Modified: 30 Jul 2024 06:09
URI: http://library.2pressrelease.co.in/id/eprint/721

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