Insecticide Susceptibility Profile of Malaria Vector Populations from the Coastal and Mainland Areas of Akwa Ibom State, Nigeria

Atting, I. A. and Ekpo, N. D. and Akpan, M. E. and Bassey, B. E. and Asuquo, M. J. and Usip, L. P. E. and Inyama, P. U. and Samdi, L. M. (2019) Insecticide Susceptibility Profile of Malaria Vector Populations from the Coastal and Mainland Areas of Akwa Ibom State, Nigeria. Journal of Advances in Medicine and Medical Research, 29 (7). pp. 1-11. ISSN 2456-8899

[thumbnail of Atting2972019JAMMR48612.pdf] Text
Atting2972019JAMMR48612.pdf - Published Version

Download (384kB)

Abstract

Development of resistance by different malaria vector populations to insecticides has become a big threat to malaria vector elimination. This study evaluated the susceptibility of Anopheles mosquito populations in Akwa Ibom State, Nigeria to permethrin (0.75%), deltamethrin (0.5%), lambdacyhalothrin (0.5%), alphacypermethrin (0.75%), Dichlorodiphenyltrichloethane (DDT), propoxur, bendiocarb and pirimiphosmethylin in World Health Organization (WHO) test tubes following standard protocols. The mosquitoes were obtained as aquatic forms and reared under laboratory conditions to adults. The adults were subjected to WHO susceptibility bioassays following standard procedures. Malaria vectors across the study sites were resistant to permethrin, deltamethrin, lambdacyhalothrin and alphacypermethrin insecticides. Full susceptibility to propoxur and bendiocarb was recorded across the sites. Full susceptibility to pirimiphosmethyl was recorded in populations from three sites. Nevertheless, population of the malaria vectors collected from Oron was resistant to pirimiphosmethyl. KDT50 and KDT95 estimated for each insecticide using a log-time probit model revealed that knockdown was more rapid for deltamethrin, lambdacyhalothrin, alphacypermethrin, propoxur, bendiocarb and pirimiphosmethyl than for DDT and permethrin across the study sites. Morphological identification of all the mosquito samples used revealed that they were female Anopheles gambiae s.l. Sustained susceptibility of malaria vectors to pyrethriod is necessary for successful malaria control with insecticide treated nets and Indoor Residual Spraying (IRS). Emergence of focal points with insecticide resistance gives serious concern especially with the scale-up in distribution of pyrethriod treated nets to these areas. This may increase selection pressures due to overexposure. Further study to identify the exact resistance mechanism(s) of malaria vectors from these sites is recommended.

Item Type: Article
Subjects: Open Archive Press > Medical Science
Depositing User: Unnamed user with email support@openarchivepress.com
Date Deposited: 04 Apr 2023 05:51
Last Modified: 20 Mar 2024 04:50
URI: http://library.2pressrelease.co.in/id/eprint/791

Actions (login required)

View Item
View Item